Data/hora: 28/05/2024 15:27:37

Provedor de dados: | Brazilian Journal of Microbiology
País: | Brazil
Título: | Phenotypic and genotypic characterization of Streptococcus agalactiae in pregnant women: first study in a province of Argentina
Autores: | Oviedo,P; Pegels,E; Laczeski,M; Quiroga,M; Vergara,M.
Data: | 2013-01-01
Ano: | 2013
Palavras-chave: | Colonization; Serotypes; Phenotypes; Virulence genes.
Resumo: | Group B Streptococcus (GBS) is the leading cause of neonatal infections. Our purpose was to characterize GBS colonization in pregnant women, current serotypes, resistance phenotypes and genes associated with virulence. In Misiones, Argentina, there are no previous data on this topic. Vaginal-rectal swabs from 3125 pregnant women were studied between 2004 and 2010. GBS strains were identified by conventional and serological methods (Phadebact Strep B Test, ETC International, Bactus AB, Sweden). Serotypes were detected using Strep-B Latex (Statens Serum Institut, Denmark). Resistance phenotypes were determined by the double-disk test. Genes were studied by PCR. Maternal colonization was 9.38%. Resistance to erythromycin was 11.6%, and the constitutive phenotype was the predominant one. Serotype Ia was the most frequent, whereas serotypes IV, VI, VII and VIII were not detected. The lmb, bca and hylB genes were detected in more than 79% of the strains. In this study, the colonization rate with GBS and the serotype distribution were compared with studies reported in other areas of the country. The high resistance to erythromycin in Misiones justifies performing antibiotic susceptibility testing. The serotype distribution, the genes encoding putative virulence factors, and the patterns of resistance phenotypes of GBS may vary in different areas. They thus need to be evaluated in each place to devise strategies for prevention.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000100036
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S1517-83822013005000030
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.44 n.1 2013
Fonte: | info:eu-repo/semantics/openAccess