Data/hora: 08/06/2024 11:51:09

Provedor de dados: 	Brazilian Journal of Microbiology	
País: 	Brazil	
Título: 	Antibacterial activity of orsellinates	
Autores: 	Gomes,Alcir Teixeira; Smania Júnior,Artur; Seidel,Cintia; Smania,Elza de Fátima Albino; Honda,Neli Kika; Roese,Fernanda Mesquita; Muzzi,Rozanna Marques.	
Data: 	2003-07-01	
Ano: 	2003	
Palavras-chave: 	Orsellinates; Lecanoric acid; Orsellinic acid; Antibacterial activity.	
Resumo: 	In order to obtain new compounds with antibacterial activity, the derivatives 2,4-dihydroxy-6-methylbenzoic acid (orsellinic acid) and 2,4-dihydroxy-6-methylbenzoates (orsellinates) were obtained through alcoholyses of lecanoric acid. All these substances were tested against Gram-positive and Gram-negative bacteria by a microdilution method. Staphylococcus aureus, Xanthomonas campestris var. vesicatoria and Ralstonia solanacearum were most sensitive to n-propyl 2,4-dihydroxy-6-methylbenzoate, n-pentyl 2,4-dihydroxy-6-methylbenzoate and n-hexyl 2,4-dihydroxy-6-methylbenzoate with MIC (Minimal Inhibitory Concentration) values ranging from 62.5 to 7.8 µg×mL¹. These results showed that homologation in carbon chain may lead to compounds with more pronunced activities.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822003000300002	
Editor: 	Sociedade Brasileira de Microbiologia	
Relação: 	10.1590/S1517-83822003000300002	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Microbiology  v.34 n.3 2003	
Fonte: 	info:eu-repo/semantics/openAccess