Data/hora: 11/06/2024 08:05:49

Provedor de dados: | Brazilian Journal of Microbiology
País: | Brazil
Título: | Mobile genetic elements related to carbapenem resistance in Acinetobacter baumannii
Autores: | Pagano,Mariana; Martins,Andreza Francisco; Barth,Afonso Luis.
Data: | 2016-12-01
Ano: | 2016
Palavras-chave: | Acinetobacter baumannii; Antimicrobial resistance; Mobile genetic elements; Carbapenem resistance.
Resumo: | Abstract Acinetobacter baumannii is widely recognized as an important pathogen associated with nosocomial infections. The treatment of these infections is often difficult due to the acquisition of resistance genes. A. baumannii presents a high genetic plasticity which allows the accumulation of these resistance determinants leading to multidrug resistance. It is highlighted the importance of the horizontal transfer of resistance genes, through mobile genetic elements and its relationship with increased incidence of multidrug resistant A. baumannii in hospitals. Considering that resistance to carbapenems is very important from the clinical and epidemiological point of view, the aim of this article is to present an overview of the current knowledge about genetic elements related to carbapenem resistance in A. baumannii such as integrons, transposons, resistance islands and insertion sequences.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000400785
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1016/j.bjm.2016.06.005
Formato: | text/html
Fonte: | Brazilian Journal of Microbiology  v.47 n.4 2016
Fonte: | info:eu-repo/semantics/openAccess