Data/hora: 08/06/2024 13:38:28

Provedor de dados: | 59
País: | Brazil
Título: | Bovine S protein (vitronectin) increases phagocytosis of Streptococcus dysgalactiae
Autores: | Filippsen,Laerte Francisco.
Data: | 1999-01-01
Ano: | 1999
Palavras-chave: | Streptococcus dysgalactiae; Bovine S protein; Phagocytosis; Bovine mastitis.
Resumo: | The effects of bovine S protein (vitronectin) on phagocytosis of Streptococcus dysgalactiae strains isolated from cattle with mastitis were investigated. Phagocytized streptococci were determined by a fluorometric microassay using glass adherent polymorphonuclear neutrophils (PMN). Preincubation of S. dysgalactiae with bovine S protein significantly increased their phagocytosis by PMN. Bovine S protein had no effect on phagocytic killing of non-S protein binding S. pyogenes cultures. Enzymatic digestion of the bovine S protein binding sites on S. dysgalactiae with pronase resulted in a significative reduction of the effects of S protein on phagocytosis. It could thus be concluded that in addition to its role as a promoter of cellular adhesion and complement inhibitor, bovine S protein may also influence the phagocytosis of S. dysgalactiae during inflammatory processes.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141999000100003
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S0001-37141999000100003
Formato: | text/html
Fonte: | Revista de Microbiologia  v.30 n.1 1999
Fonte: | info:eu-repo/semantics/openAccess