Data/hora: 09/06/2024 14:57:31

Provedor de dados: | 59
País: | Brazil
Título: | Drug resistance of yeasts isolated from oropharyngeal candidiasis in aids patients
Autores: | Silva,Maria do Rosário Rodrigues; Paula,Claudete Rodrigues de; Silva,Soraya Cristina; Costa,Théo Rodrigues; Costa,Márcio Rodrigues.
Data: | 1998-10-01
Ano: | 1998
Palavras-chave: | Oropharyngeal candidiasis; Yeasts; In vitro resistance; Antifungal drugs.
Resumo: | Candida spp was isolated from 59 (68.60%) out of eighty six samples of oral mucosa of AIDS patients. The identification, based or the production of a germ tube and chlamydospores, and on the assimilation and fermentation of carbohydrates, revealed 52 strains (88.13%) of C. albicans, 4 (6.77%) of C. tropicalis and 3 (5.08%) of C. krusei. The susceptibility of these strains to amphotericin B, flucytosine, itraconazole, fluconazole and ketoconazole was determined using the agar dilution method. Comparing the minimum inhibitory concentration values found in the susceptibility test with the serum levels achieved by these drugs, only 8.47% and 5.08% of the yeasts strains proved to be resistant to amphotericin B and flucitosyne, respectively. A high frequency of strains resistant to azole derivatives (25.42%, to itraconazole, 45.76%, to ketoconazole and 66.10% to fluconazole) was observed.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141998000400007
Editor: | Sociedade Brasileira de Microbiologia
Relação: | 10.1590/S0001-37141998000400007
Formato: | text/html
Fonte: | Revista de Microbiologia  v.29 n.4 1998
Fonte: | info:eu-repo/semantics/openAccess