Data/hora: 09/06/2024 16:58:55

Provedor de dados: | 60
País: | Brazil
Título: | Quercetin: a flavonoid with the potential to treat asthma
Autores: | Fortunato,Laila Rigolin; Alves,Claudiney de Freitas; Teixeira,Maxelle Martins; Rogerio,Alexandre Paula.
Data: | 2012-12-01
Ano: | 2012
Palavras-chave: | Quercetin; Flavonoids; Asthma.
Resumo: | Allergic asthma is a complex inflammatory disorder characterized by airway hyperresponsiveness, eosinophilic inflammation and hypersecretion of mucus. Current therapies include β2-agonists, cysteinyl leukotriene receptor 1 antagonists and corticosteroids. Although these drugs demonstrate beneficial effects, their adverse side effects limit their long-term use. Thus, the development of new compounds with similar therapeutic activities and reduced side effects is both desirable and necessary. Natural compounds are used in some current therapies, as plant-derived metabolites can relieve disease symptoms in the same manner as allopathic medicines. Quercetin is a flavonoid that is naturally found in many fruits and vegetables and has been shown to exert multiple biological effects in experimental models, including the reduction of major symptoms of asthma: bronchial hyperactivity, mucus production and airway inflammation. In this review, we discuss results from the literature that illustrate the potential of quercetin to treat asthma and its exacerbations.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000400002
Editor: | Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação: | 10.1590/S1984-82502012000400002
Formato: | text/html
Fonte: | Brazilian Journal of Pharmaceutical Sciences  v.48 n.4 2012
Fonte: | info:eu-repo/semantics/openAccess