Data/hora: 16/06/2024 03:53:28

Provedor de dados: 	60	
País: 	Brazil	
Título: 	Antidiabetic and antihyperlipidemic effects of Dillenia indica (L.) leaves extract	
Autores: 	Kumar,Sunil; Kumar,Vipin; Prakash,Om.	
Data: 	2011-06-01	
Ano: 	2011	
Palavras-chave: 	Dillenia indica/antidiabetic effects; Dillenia indica/experimental study; Dillenia indica/antihyperlipidemic effects; Dillenia indica/experimental study; Antidiabetics/experimental study; Serum transaminase; Serum cholesterol; HDL-cholesterol level.	
Resumo: 	The present study was carried out to evaluate antidiabetic and antihyperlipidemic effects of Dillenia indica methanolic leaves extracts in streptozotocin induced diabetic Wistar rats by administering graded oral doses (250 and 500 mg/kg body weight) for 21 days. The extract showed significant antidiabetic activity (p&lt;0.001). Furthermore, the decreased body weight of rats was significantly improved after extract treatments. Daily oral treatment with the extract for 21 days to diabetic rats, also resulted in significant reduction in serum cholesterol, triglycerides and serum transaminase levels but HDL-cholesterol level was found to be improved (p&lt;0.001) as compared to the diabetic control group. The extract treatment also showed to enhance serum insulin level in diabetic rats as compared to the diabetic control group. In conclusion, D. indica leaf extract might be useful for diabetes mellitus management and other abnormalities associated with this metabolic disorder.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200018	
Editor: 	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas	
Relação: 	10.1590/S1984-82502011000200018	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Pharmaceutical Sciences  v.47 n.2 2011	
Fonte: 	info:eu-repo/semantics/openAccess