Data/hora: 06/06/2024 04:25:06

Provedor de dados: 	60	
País: 	Brazil	
Título: 	Production and characterization of alginate-starch-chitosan microparticles containing stigmasterol through the external ionic gelation technique	
Autores: 	Fujiwara,Gislene Mari; Campos,Ranieri; Costa,Camila Klocker; Dias,Josiane de Fátima Gaspari; Miguel,Obdulio Gomes; Miguel,Marilis Dallarmi; Marques,Francisco de Assis; Zanin,Sandra Maria Warumby.	
Data: 	2013-09-01	
Ano: 	2013	
Palavras-chave: 	Stigmasterol/microencapsulation; Microencapsulation; Sodium alginate/drugs coating; Chitosan/drugs coating; Starch/drugs coating; Natural polymers/drugs coating.	
Resumo: 	Stigmasterol - a plant sterol with several pharmacological activities - is susceptible to oxidation when exposed to air, a process enhanced by heat and humidity. In this context, microencapsulation is a way of preventing oxidation, allowing stigmasterol to be incorporated into various pharmaceutical forms while increasing its absorption. Microparticles were obtained using a blend of polymers of sodium alginate, starch and chitosan as the coating material through a one-stage process using the external gelation technique. Resultant microparticles were spherical, averaging 1.4 mm in size. Encapsulation efficiency was 90.42% and method yield 94.87%. The amount of stigmasterol in the oil recovered from microparticles was 9.97 mg/g. This technique proved feasible for the microencapsulation of stigmasterol.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000300015	
Editor: 	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas	
Relação: 	10.1590/S1984-82502013000300015	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Pharmaceutical Sciences  v.49 n.3 2013	
Fonte: 	info:eu-repo/semantics/openAccess