Data/hora: 10/06/2024 14:04:04

Provedor de dados: | 60
País: | Brazil
Título: | Alginate-pomegranate peels' polyphenols beads: effects of formulation parameters on loading efficiency
Autores: | Zam,Wissam; Bashour,Ghada; Abdelwahed,Wassim; Khayata,Warid.
Data: | 2014-12-01
Ano: | 2014
Palavras-chave: | Pomegranate/polyphenols/microencapsulation; Calcium alginate beads/microencapsulation; Microencapsulation; Polyphenols; Natural antioxidants/microencapsulation.
Resumo: | Calcium alginate beads containing pomegranate peels' polyphenol extract were encapsulated by ionic gelation method. The effects of various formulation factors (sodium alginate concentration, calcium chloride concentration, calcium chloride exposure time, gelling bath time maintaining, and extract concentration) on the efficiency of extract loading were investigated. The formulation containing an extract of 1 g pomegranate peels in 100 mL distilled water encapsulated with 3 % of sodium alginate cured in 0.05 M calcium chloride for 20 minutes and kept in a gelling bath for 15 minutes was chosen as the best formula regarding the loading efficiency. These optimized conditions allowed the encapsulation of 43.90% of total extracted polyphenols and 46.34 % of total extracted proanthocyanidins. Microencapsulation of pomegranate peels' extract in calcium alginate beads is a promising technique for pharmaceutical and food supplementation with natural antioxidants.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400741
Editor: | Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Relação: | 10.1590/S1984-82502014000400009
Formato: | text/html
Fonte: | Brazilian Journal of Pharmaceutical Sciences  v.50 n.4 2014
Fonte: | info:eu-repo/semantics/openAccess