Data/hora: 09/06/2024 13:32:13

Provedor de dados: 	60	
País: 	Brazil	
Título: 	Ethanolic extract of Passiflora edulis Sims leaves inhibits protein glycation and restores the oxidative burst in diabetic rat macrophages after Candida albicans exposure	
Autores: 	Martins,Carolina Fernandes Ribas; Salles,Bruno César Corrêa; Brigagão,Maisa Ribeiro Pereira Lima; Rodrigues,Maria Rita; Ferreira,Eric Batista; Duarte,Stella Maris da Silveira; Paula,Fernanda Borges de Araujo.	
Data: 	2015-12-01	
Ano: 	2015	
Palavras-chave: 	Passiflora edulis Sims/pharmacognosy; Passiflora edulis Sims/ethanolic extract/effects; Blood glucose; Protein glycation; Reactive oxygen species; Diabetes/treatment/experimental study; Medicinal plants.	
Resumo: 	abstract This study was conducted to evaluate the effects of the ethanolic extract of Passiflora edulis leaves on blood glucose, protein glycation, NADPH oxidase activity and macrophage phagocytic capacity after Candida albicans exposure in diabetic rats. The Passiflora edulis Sims leaves were dried to 40°C, powdered, extracted by maceration in 70% ethanol, evaporated under reduced pressure and lyophilised. The biochemical tests performed were total phenolic content (TP) as determined by the Folin-Ciocalteu assay, trapping potential DPPH assay and total iron-reducing potential. Diabetes was induced by alloxan injection. Protein glycation was determined by AGE and fructosamine serum concentrations. Extract-treated diabetic animals demonstrated lower fructosamine concentrations compared with the diabetic group. Our results suggest that ethanolic Passiflora edulis Sims leaf extraction may have beneficial effects on diabetes and may improve glycaemic control in diabetic rats.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000400869	
Editor: 	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas	
Relação: 	10.1590/S1984-82502015000400013	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Pharmaceutical Sciences  v.51 n.4 2015	
Fonte: 	info:eu-repo/semantics/openAccess