Data/hora: 02/06/2024 05:15:11

Provedor de dados: | Brazilian Jounarl of Veterinary
País: | Brazil
Título: | Baypamun® action in hamsters experimentally infected with Leptospira interrogans serogroup Canicola
Autores: | LANGONI,Hélio; SEABRA JÚNIOR,Rui; CABRAL,Kenio Gouveia; CUNHA,Eva Laurice Pereira.
Data: | 2001-01-01
Ano: | 2001
Palavras-chave: | Immunomodulators; Leptospira; Immunity.
Resumo: | Baypamun® is an immunity modulator recommended as prophylactic and therapeutic use. In the present study, this product was used in the hamsters experimentally infected with Leptospira interrogans serogroup canicola. The animals were divided in 5 groups, with 20 animals each. This product was used as a therapeutic, prophylactic and as adjuvant. As a therapeutic use all the animals died. Despite of eight (40.0%) survivors, the prophylactic use wasn't also totally favorable due to leptospire recovering from kidneys of those animals. Based on the analysis of antibodies levels among animals that received vaccine and vaccine with Baypamun® as adjuvante, this product didn't conferred superior humoral answer. However, other studies should be accomplished utilizing this product in a longer period as well as verify the cellular answer by Baypamun® use as adjuvant in the infectious disease.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962001000600010
Editor: | Faculdade de Medicina Veterinária e Zootecnia / Universidade de São Paulo
Relação: | 10.1590/S1413-95962001000600010
Formato: | text/html
Fonte: | Brazilian Journal of Veterinary Research and Animal Science  v.38 n.6 2001
Fonte: | info:eu-repo/semantics/openAccess