Data/hora: 09/06/2024 18:23:43

Provedor de dados: | 62
País: | Brazil
Título: | Chloramphenicol restores the polymorphonuclear accumulation in carrageenin-induced pleurisy in diabetic rats
Autores: | MORAES,Julieta Rodini Engrácia de; MORAES,Flávio Ruas de; ENGRÁCIA FILHO,Jair Rodini.
Data: | 1998-01-01
Ano: | 1998
Palavras-chave: | Chloramphenicol; Diabetes; Pleurisia; Neutrophils.
Resumo: | We investigated the effect of chloramphenicol succinate (30 mg/kg, every 12 h for 4 days, ip) on the reduced polymorphonuclear leukocytes (PMN) accumulation in carrageenin-induced pleurisy (150 mug) in diabetic (alloxan, 40 mg/kg, IV) rats (Wistar, males, 180-320 g, n = 12). Chloramphenicol produced an increase (p&lt;0.05) on PMN count in pleural exudate of 36% in normal animals. In the animals non-treated with chloramphenicol the diabetes state reduced (p&lt;0.05) the accumulation of PMN cells by 45%. In diabetic animals treated with chloramphenicol the number of PMN in pleural exudate was similar to the one observed in the control group. Total and differential counts of leukocytes in the peripheral blood were similar between groups before and 4 h after the carrageenin-injection.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95961998000600002
Editor: | Faculdade de Medicina Veterinária e Zootecnia / Universidade de São Paulo
Relação: | 10.1590/S1413-95961998000600002
Formato: | text/html
Fonte: | Brazilian Journal of Veterinary Research and Animal Science  v.35 n.6 1998
Fonte: | info:eu-repo/semantics/openAccess