Data/hora: 09/06/2024 16:05:36

Provedor de dados: | 65
País: | Brazil
Título: | Synovial fluid as an auxiliary diagnostic tool for different stages of canine visceral leishmaniasis
Autores: | Rennó,Mário César; Vasconcellos,Amanda Otoni; Santos,Rogerio Rodrigues; Silva,Rodrigo Otávio Silveira; Carneiro,Rubens Antônio; Paes,Paulo Ricardo de Oliveira.
Data: | 2019-01-01
Ano: | 2019
Palavras-chave: | Leishmania infantum; Zoonosis.
Resumo: | ABSTRACT:  Leishmaniasis represents a complex of chronic diseases with a broad geographic distribution and a high significance in public health worldwide. The varied clinical signs in conjunction with the low sensitivity and specificity of canine visceral leishmaniasis (CVL) detection methods make diagnosis of the disease complex. Among the several available laboratory tests, studies have suggested that the detection of parasites in synovial fluid (SF) is a good auxiliary tool in the diagnosis of CVL. However, no study has evaluated the influence of the clinical stage of CVL in the detection of Leishmania sp. in SF. This study aimed to evaluate the detection of Leishmania sp. amastigotes in the SF of dogs at different stages of the disease. The negative control group (G1) comprised 12 dogs that tested negative for CVL. Thirty-six other dogs, tested serologically positive for CVL, were divided into two groups: Group 2 (G2), which included animals at stage II of the disease (moderate; n=18), and Group 3 (G3) included animals at stage III of the disease (severe; n=18). The analysis of SF revealed the presence of parasites in six (33.3%) dogs from G2 and in 16 (88.9%) dogs from G3 (p=0.0437). The present research suggested that SF analysis is of high value as a supplementary tool in the diagnosis of CVL. As a new finding, the present study also indicated that this test has a higher sensitivity in animals presenting with more severe stage of the disease.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000500901
Editor: | Universidade Federal de Santa Maria
Relação: | 10.1590/0103-8478cr20190023
Formato: | text/html
Fonte: | Ciência Rural  v.49 n.5 2019
Fonte: | info:eu-repo/semantics/openAccess