Data/hora: 10/06/2024 09:02:51

Provedor de dados: | Electronic Journal of Biotechnology
País: | Chile
Título: | In vivo assessment of possible probiotic properties of Zymomonas mobilis in a Wistar rat model
Autores: | Azerêdo,Geíza Alves de; Stamford,Tânia Lúcia Montenegro; Souza,Evandro Leite de; Veras,Flávio Fonseca; Almeida,Edvaldo Rodrigues de; Araújo,Janete Magali de.
Data: | 2010-03-01
Ano: | 2010
Palavras-chave: | Health benefit; Safety; Zymomonas mobilis.
Resumo: | In recent years the incorporation of probiotic bacteria into foods has received increasing scientific interest for health promotion and disease prevention. The safety and probiotic properties of Zymomonas mobilis CP4 (UFPEDA-202) was studied in a Wistar rat model fed the 10(9) colony forming units (cfu)/mL-1 of the assayed strain for 30 days. No abnormal clinical signs were noted in the group receiving viable cells of Z. mobilis and water (control) during the period of the experiment. There were no significant difference (p &gt; 0.05) in feed intake and weight gain among mice fed the Z. mobilis in comparison to the control group. No bacteria were found in blood, liver and spleen of any animals. Mice receiving Z. mobilis showed significantly differences (p &lt; 0.05) in total and differential leucocytes count, excepting for neutrophils, after the experimental period. Otherwise, it was not found in control group. Histological examination showed that feeding mice with Z. mobilis caused no signs of adverse effects on gut, liver and spleen. From these results, Z. mobilis CP4 (UFEPEDA-202) is likely to be nonpathogenic and safe for consumption, and could have a slight modulating effect on immunological performance in mice.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582010000200003
Editor: | Pontificia Universidad Católica de Valparaíso
Formato: | text/html
Fonte: | Electronic Journal of Biotechnology  v.13 n.2 2010