Data/hora: 16/06/2024 06:37:15

Provedor de dados: | 69
País: | Chile
Título: | Novel antiviral activity of dialdehyde starch
Autores: | Song,Le; Cruz,Caroline; Farrah,Samuel R; Baney,Ronald H.
Data: | 2009-04-01
Ano: | 2009
Palavras-chave: | Antiviral; Biocide; Dialdehyde starch; Virus.
Resumo: | A significant effort worldwide is being directed toward development of novel biocides against drug-resistant bacterial and viruses because of the significant potential human infection risks in the general population. We report here the discovery of a strong antiviral biocide, dialdheyde starch (DAS). Antiviral tests were carried out against three non-envelop viruses, including two bacterial viruses MS2 and PRD1, and one human virus Poliovirus. Dialdehyde starch aqueous suspensions were effective biocides against these three test viruses in a 1 hr exposure test. The antiviral activity was significantly enhanced in a four-hour exposure test, with maximum seven orders of magnitude reductions against MS2 and PRD1, and four-order reduction against Poliovirus. The antiviral activity of dialdehyde starch was found to be pH dependent, being more active in alkaline and acidic conditions than in neutral conditions.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582009000200013
Editor: | Pontificia Universidad Católica de Valparaíso
Formato: | text/html
Fonte: | Electronic Journal of Biotechnology  v.12 n.2 2009