Data/hora: 10/06/2024 17:18:22

Provedor de dados: | Ecology and Society
País: | Canada
Título: | The Mathematical Biology of Human Infections
Autores: | Nowak, Martin A; Institute for Advanced Study; nowak@ias.edu.
Data: | 1999-11-10
Ano: | 1999
Palavras-chave: | CTL response; HIV; Antivirals; Epidemiology; Immune response; Infectious diseases; Mathematical biology; Models of evolution; Prions; Resistance; Treatment; Viruses.
Resumo: | Humans are constant victims of infectious diseases. Biomedical research during this century has led to important insights into the molecular details of immune defense. Yet, many questions relating to disease require a quantitative understanding of the complex systems that arise from the nonlinear interactions between populations of immune cells and infectious agents. Exploration of such questions has lead to a newly emerging field of mathematical biology describing the spread of infectious agents both within and between infected individuals. This essay will discuss simple and complex models of evolution, and the propagation of virus and prion infections. Such models provide new perspectives for our understanding of infectious disease and provide guidelines for interpreting experimental observation; they also define what needs to be measured to improve understanding.
Tipo: | Peer-Reviewed Reports
Idioma: | Inglês
Identificador: | vol3/iss2/art12/
Editor: | Resilience Alliance
Formato: | text/html
Fonte: | Ecology and Society; Vol. 3, No. 2 (1999)