Data/hora: 04/06/2024 05:26:12

Provedor de dados: 	74	
País: 	Brazil	
Título: 	Costs of genetic testing: Supporting Brazilian Public Policies for the incorporating of molecular diagnostic technologies	
Autores: 	Schlatter,Rosane Paixão; Matte,Ursula; Polanczyk,Carisi Anne; Koehler-Santos,Patrícia; Ashton-Prolla,Patricia.	
Data: 	2015-09-01	
Ano: 	2015	
Palavras-chave: 	Molecular diagnosis; Hereditary cancer; Cost analysis.	
Resumo: 	This study identifies and describes the operating costs associated with the molecular diagnosis of diseases, such as hereditary cancer. To approximate the costs associated with these tests, data informed by Standard Operating Procedures for various techniques was collected from hospital software and a survey of market prices. Costs were established for four scenarios of capacity utilization to represent the possibility of suboptimal use in research laboratories. Cost description was based on a single site. The results show that only one technique was not impacted by rising costs due to underutilized capacity. Several common techniques were considerably more expensive at 30% capacity, including polymerase chain reaction (180%), microsatellite instability analysis (181%), gene rearrangement analysis by multiplex ligation probe amplification (412%), non-labeled sequencing (173%), and quantitation of nucleic acids (169%). These findings should be relevant for the definition of public policies and suggest that investment of public funds in the establishment of centralized diagnostic research centers would reduce costs to the Public Health System.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000300332	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-475738320140204	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.38 n.3 2015	
Fonte: 	info:eu-repo/semantics/openAccess