Data/hora: 10/06/2024 00:39:10

Provedor de dados: 	Genetics and Molecular Biology	
País: 	Brazil	
Título: 	Three novel polymorphic microsatellite markers for the glaucoma locus GLC1B by datamining tetranucleotide repeats on chromosome 2p12-q12	
Autores: 	Murga-Zamalloa,Carlos; Guevara-Fujita,Maria Luisa; Estrada-Cuzcano,Alejandro; Fujita,Ricardo.	
Data: 	2009-01-01	
Ano: 	2009	
Palavras-chave: 	GLC1B; Microsatellite polymorphic markers; Tetranucleotide tandem repeat; Gene mapping; Glaucoma.	
Resumo: 	In order to identify new markers around the glaucoma locus GLC1B as a tool to refine its critical region at 2p11.2-2q11.2, we searched the critical region sequence obtained from the UCSC database for tetranucleotide (GATA)n and (GTCT)n repeats of at least 10 units in length. Three out of four potential microsatellite loci were found to be polymorphic, heterozygosity ranging from 64.56% to 79.59%. The identified markers are useful not only for GLC1B locus but also for the study of other disease loci at 2p11.2-2q11.2, a region with scarcity of microsatellite markers.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400009	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572009005000093	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.32 n.4 2009	
Fonte: 	info:eu-repo/semantics/openAccess