Data/hora: 29/05/2024 05:47:28

Provedor de dados: | Genetics and Molecular Biology
País: | Brazil
Título: | Alternative parameterizations of relatedness in whole genome association analysis of pre-weaning traits of Nelore-Angus calves
Autores: | Riley,David G.; Gill,Clare A.; Herring,Andy D.; Riggs,Penny K.; Sawyer,Jason E.; Sanders,James O.
Data: | 2014-09-01
Ano: | 2014
Palavras-chave: | Birth weight; Gestation length; Weaning weight; Nelore; Whole genome association.
Resumo: | Gestation length, birth weight, and weaning weight of F2 Nelore-Angus calves (n = 737) with designed extensive full-sibling and half-sibling relatedness were evaluated for association with 34,957 SNP markers. In analyses of birth weight, random relatedness was modeled three ways: 1) none, 2) random animal, pedigree-based relationship matrix, or 3) random animal, genomic relationship matrix. Detected birth weight-SNP associations were 1,200, 735, and 31 for those parameterizations respectively; each additional model refinement removed associations that apparently were a result of the built-in stratification by relatedness. Subsequent analyses of gestation length and weaning weight modeled genomic relatedness; there were 40 and 26 trait-marker associations detected for those traits, respectively. Birth weight associations were on BTA14 except for a single marker on BTA5. Gestation length associations included 37 SNP on BTA21, 2 on BTA27 and one on BTA3. Weaning weight associations were on BTA14 except for a single marker on BTA10. Twenty-one SNP markers on BTA14 were detected in both birth and weaning weight analyses.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572014000400007
Editor: | Sociedade Brasileira de Genética
Relação: | 10.1590/S1415-47572014000400007
Formato: | text/html
Fonte: | Genetics and Molecular Biology  v.37 n.3 2014
Fonte: | info:eu-repo/semantics/openAccess