Data/hora: 09/06/2024 01:07:55

Provedor de dados: 	74	
País: 	Brazil	
Título: 	Oxytocin and arginine vasopressin systems in the domestication process	
Autores: 	Fam,Bibiana S.O.; Paré,Pamela; Felkl,Aline B.; Vargas-Pinilla,Pedro; Paixão-Côrtes,Vanessa R.; Viscardi,Lucas Henriques; Bortolini,Maria Cátira.	
Data: 	2018-01-01	
Ano: 	2018	
Palavras-chave: 	Oxytocin and receptors; Vasopressin and receptors; Animal domestication; Molecular evolution; Positive selection.	
Resumo: 	Abstract Domestication is of unquestionable importance to the technological revolution that has given rise to modern human societies. In this study, we analyzed the DNA and protein sequences of six genes of the oxytocin and arginine vasopressin systems (OXT-OXTR; AVP-AVPR1a, AVPR1b and AVPR2) in 40 placental mammals. These systems play an important role in the control of physiology and behavior. According to our analyses, neutrality does not explain the pattern of molecular evolution found in some of these genes. We observed specific sites under positive selection in AVPR1b (ω = 1.429, p = 0.001) and AVPR2 (ω= 1.49, p = 0.001), suggesting that they could be involved in behavior and physiological changes, including those related to the domestication process. Furthermore, AVPR1a, which plays a role in social behavior, is under relaxed selective constraint in domesticated species. These results provide new insights into the nature of the domestication process and its impact on the OXT-AVP system.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000200235	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/1678-4685-gmb-2017-0069	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.41 n.1 suppl.1 2018	
Fonte: 	info:eu-repo/semantics/openAccess