Data/hora: 09/06/2024 07:21:51

Provedor de dados: 	74	
País: 	Brazil	
Título: 	Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes	
Autores: 	Loreto,Elgion Lúcio Silva; Ortiz,Mauro Freitas; Porto,Jorge Ivan Rebelo.	
Data: 	2007-01-01	
Ano: 	2007	
Palavras-chave: 	Insertion sequences; IS; Mollicutes; Horizontal gene transfer; Mycoplasma.	
Resumo: 	We have analyzed the sequenced genomes of three strains of Mycoplasma hyopneumoniae and one strain of M. synoviae, and have found three and two different transposable element families, respectively in each species. In M. hyopneumoniae, the Insertion Sequences of the IS4 family is represented by ISMHp1, a putatively active element. The IS3 family is represented by several degenerated sequences. A third element called tMH was found, which shows some characteristics reminiscent of retrotransposons. In M. synoviae, three different possibly active IS4 elements are present (ISMHp1-like; ISMs1 and IS1634-like elements). The IS30 family is represented by the degenerated IS1630-like element. The IS1634-like element is shown to be involved in chromosomal rearrangements and horizontal gene transfer (HGT). The ISMHp1-like element is shown to relate to the HGT of a 25-kb region from M. gallisepticum to M. synoviae. The fractions of these genomes that correspond to mobile elements varied from 1.35 to 3.13% in M. hyopneumonia strains and was 2.08% in M. synoviae. Although these species possess reduced genomes, they maintain mobile elements, perhaps as a mechanism for genetic variability production.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200017	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572007000200017	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.30 n.1 suppl.0 2007	
Fonte: 	info:eu-repo/semantics/openAccess