Data/hora: 05/06/2024 08:08:54

Provedor de dados: 	Genetics and Molecular Biology	
País: 	Brazil	
Título: 	Effects of H2O2, Fe2+ and Fe3+ on curcumin-induced chromosomal aberrations in CHO cells	
Autores: 	Antunes,Lusânia Maria Greggi; Araújo,Maria Cristina Paiva; Dias,Francisca da Luz; Takahashi,Catarina Satie.	
Data: 	2005-03-01	
Ano: 	2005	
Palavras-chave: 	CHO; Chromosomal aberrations; Curcumin; Hydrogen peroxide; Mutagenesis.	
Resumo: 	The effects of H2O2, Fe2+ and Fe3+ on curcumin-induced clastogenicity were evaluated in CHO cells. Curcumin combined with H2O2 did not increase the chromosomal aberrations more than expected based on a simple additive effect. In contrast, the combination of curcumin-Fe significantly decreased the total number of chromosomal aberrations and the number of abnormal metaphases. The clastogenicity of curcumin may be related to its pro-oxidant properties and its ability to generate free radicals.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100028	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572005000100028	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.28 n.1 2005	
Fonte: 	info:eu-repo/semantics/openAccess