Data/hora: 06/06/2024 02:49:42

Provedor de dados: | 74
País: | Brazil
Título: | (TTTA)n polymorphism of CYP19 (aromatase gene) in Euro- and Afro-Brazilians
Autores: | Kvitko,Kátia; Nunes,Janice Corrêa de Barros; Hutz,Mara Helena.
Data: | 2004-01-01
Ano: | 2004
Palavras-chave: | CYP19; Gene polymorphism.
Resumo: | We investigated the polymorphic tetranucleotide repeat (TTTA)n located in the fourth intron of the CYP19 gene in two Brazilian populations. The frequencies of the five common alleles (A) in Euro- and Afro-Brazilians were, respectively: seven repeats (A5), 0.586 and 0.80; eight repeats (A4), 0.092 and 0.06; nine repeats (A3), 0.014 and 0.01; eleven repeats (A2), 0.284 and 0.09; twelve repeats (A1), 0.021 and 0.04. In addition, one Euro-Brazilian individual had a rare allele with 13 repeats. The allelic frequencies in Euro- and Afro-Brazilians differed statistically (p &lt; 10-3). The two samples were found to be in Hardy-Weinberg equilibrium (p = 0,828 and p = 0,995).
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000300005
Editor: | Sociedade Brasileira de Genética
Relação: | 10.1590/S1415-47572004000300005
Formato: | text/html
Fonte: | Genetics and Molecular Biology  v.27 n.3 2004
Fonte: | info:eu-repo/semantics/openAccess