Data/hora: 11/06/2024 02:22:05

Provedor de dados: | 74
País: | Brazil
Título: | In search of essentiality: Mollicute-specific genes shared by twelve genomes
Autores: | Souza,Rangel Celso; Almeida,Darcy Fontoura de; Zaha,Arnaldo; Morais,David Anderson de Lima; Vasconcelos,Ana Tereza Ribeiro de.
Data: | 2007-01-01
Ano: | 2007
Palavras-chave: | Mollicutes; Comparative genomics; Synteny; Bidirectional best hit.
Resumo: | Mollicutes are cell wall-less bacteria with a genome characterized by its small size. Chromosomal rearrangements help these organisms evade host immune surveillance and hence cause disease. Our goal was to determine genes shared by Mollicutes genomes using the bidirectional best hit methodology. The twelve studied Mollicutes share 210 genes, most of which (&gt; 60%) fall into the following COG categories: translation, ribosomal structure and biogenesis; DNA replication, recombination and repair; nucleotide transport and metabolism and energy production and conversion. Thirty Mollicute-specific genes were identified, 22 of them previously described as essential genes in Mycoplasma genitalium.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200002
Editor: | Sociedade Brasileira de Genética
Relação: | 10.1590/S1415-47572007000200002
Formato: | text/html
Fonte: | Genetics and Molecular Biology  v.30 n.1 suppl.0 2007
Fonte: | info:eu-repo/semantics/openAccess