Data/hora: 10/06/2024 06:36:28

Provedor de dados: 	74	
País: 	Brazil	
Título: 	Monosomy 7 in donor cell-derived leukemia after bone marrow transplantation for severe aplastic anemia: report of a new case and review of the literature	
Autores: 	Otero,Luize; Souza,Daiane Correa de; Tavares,Rita de Cássia; Gomes,Bernadete Evangelho; Padilha,Telma França; Bouzas,Luiz Fernando; Fernandez,Teresa de Souza; Abdelhay,Eliana.	
Data: 	2012-01-01	
Ano: 	2012	
Palavras-chave: 	Monosomy 7; Donor cell leukemia; Bone marrow transplantation; Severe aplastic anemia.	
Resumo: 	Monosomy 7 arises as a recurrent chromosome aberration in donor cell leukemia after hematopoietic stem cell transplantation. We report a new case of donor cell leukemia with monosomy 7 following HLA-identical allogenic bone marrow transplantation for severe aplastic anemia (SAA). The male patient received a bone marrow graft from his sister, and monosomy 7 was detected only in the XX donor cells, 34 months after transplantation. The patient's bone marrow microenvironment may have played a role in the leukemic transformation of the donor hematopoietic cells.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000500004	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572012005000056	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.35 n.4 2012	
Fonte: 	info:eu-repo/semantics/openAccess