Data/hora: 13/06/2024 02:22:09

Provedor de dados: | 74
País: | Brazil
Título: | Electrophoretic molecular karyotype of the dermatophyte Trichophyton rubrum
Autores: | Cervelatti,Eliane P.; Ferreira-Nozawa,Monica S.; Aquino-Ferreira,Roseli; Fachin,Ana Lúcia; Martinez-Rossi,Nilce M.
Data: | 2004-01-01
Ano: | 2004
Palavras-chave: | Trichophyton rubrum; Fungal chromosomes; Electrophoretic karyotype; Dermatophyte; Contour-clamped homogeneous electric field.
Resumo: | The electrophoretic karyotype of the dermatophyte Trichophyton rubrum was established using contour-clamped homogeneous electric field (CHEF) gel electrophoresis. Five chromosomal bands of approximately 3.0 to 5.8 megabase pairs (Mbp) each were observed and together indicated that 22.05 Mbp of the total genome are organized as chromosomal macromolecules. In addition to establishing the number and size of T. rubrum chromosomes, these results open perspectives for the construction of chromosome-specific libraries and for the physical mapping of genes of interest, thus permitting future gene linkage studies in this pathogen. A detailed understanding of the karyotype and genomic organization of T. rubrum should contribute to further genetic, taxonomic and epidemiological studies of this dermatophyte.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000100016
Editor: | Sociedade Brasileira de Genética
Relação: | 10.1590/S1415-47572004000100016
Formato: | text/html
Fonte: | Genetics and Molecular Biology  v.27 n.1 2004
Fonte: | info:eu-repo/semantics/openAccess