Data/hora: 18/06/2024 09:55:36

Provedor de dados: | 74
País: | Brazil
Título: | Distribution of glutathione S-transferase GSTM1 and GSTT1 null phenotypes in Brazilian Amerindians
Autores: | Klautau-Guimarães,Maria de Nazaré; Hiragi,Cássia de Oliveira; D'Ascenção,Renata Ferreira; Oliveira,Silviene Fabiana; Grisolia,Cesar Koppe; Hatagima,Ana; Ferrari,Íris.
Data: | 2005-03-01
Ano: | 2005
Palavras-chave: | Munduruku; Glutathione S-transferase; Kayabi; Null alleles.
Resumo: | The distribution of glutathione S-transferase (GST) GSTM1 and GSTT1 null phenotype frequencies in two Brazilian Amerindian tribes, the Munduruku tribe from Missão Cururu village (79 individuals) and the Kayabi tribe (41 individuals), was analyzed by polymerase chain reaction (PCR) amplification. The GST null phenotype frequencies for the Munduruku sample were 0% for GSTM1 and 27% for GSTT1 while for the Kayabi sample the null phenotype frequencies were 27% for GSTM1 and 29% for GSTT1. This is the first report of the absence of the GSTM1 null phenotype in any ethnic group.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000100005
Editor: | Sociedade Brasileira de Genética
Relação: | 10.1590/S1415-47572005000100005
Formato: | text/html
Fonte: | Genetics and Molecular Biology  v.28 n.1 2005
Fonte: | info:eu-repo/semantics/openAccess