Data/hora: 06/06/2024 02:19:33

Provedor de dados: 	Genetics and Molecular Biology	
País: 	Brazil	
Título: 	Investigations on DNA damage and frequency of micronuclei in occupational exposure to electromagnetic fields (EMFs) emitted from video display terminals (VDTs)	
Autores: 	Lakshmi,NK; Tiwari,R; Bhargava,SC; Ahuja,YR.	
Data: 	2010-01-01	
Ano: 	2010	
Palavras-chave: 	Electromagnetic fields (EMFs); Video display terminals (VDTs); Comet assay; DNA damage; Micronuclei.	
Resumo: 	The potential effect of electromagnetic fields (EMFs) emitted from video display terminals (VDTs) to elicit biological response is a major concern for the public. The software professionals are subjected to cumulative EMFs in their occupational environments. This study was undertaken to evaluate DNA damage and incidences of micronuclei in such professionals. To the best of our knowledge, the present study is the first attempt to carry out cytogenetic investigations on assessing bioeffects in personal computer users. The study subjects (n = 138) included software professionals using VDTs for more than 2 years with age, gender, socioeconomic status matched controls (n = 151). DNA damage and frequency of micronuclei were evaluated using alkaline comet assay and cytochalasin blocked micronucleus assay respectively. Overall DNA damage and incidence of micronuclei showed no significant differences between the exposed and control subjects. With exposure characteristics, such as total duration (years) and frequency of use (minutes/day) sub-groups were assessed for such parameters. Although cumulative frequency of use showed no significant changes in the DNA integrity of the classified sub-groups, the long-term users (&gt; 10 years) showed higher induction of DNA damage and increased frequency of micronuclei and micro nucleated cells.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000100026	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572010005000010	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.33 n.1 2010	
Fonte: 	info:eu-repo/semantics/openAccess