Data/hora: 10/06/2024 00:38:05

Provedor de dados: | Genetics and Molecular Biology
País: | Brazil
Título: | Beta-globin gene cluster haplotypes in Venezuelan sickle cell patients from the State of Aragua
Autores: | Moreno,Nancy; Martínez,José A.; Blanco,Zorella; Osorio,Leidys; Hackshaw,Patrick.
Data: | 2002-01-01
Ano: | 2002
Palavras-chave: | Haplotypes; Beta-globin gene cluster; Sickle cell.
Resumo: | Seven polymorphic sites in the beta-globin gene cluster were analyzed on a sample of 96 chromosomes of Venezuelan sickle cell patients from the State of Aragua. The Benin haplotype was predominant with a frequency of 0.479, followed by the Bantu haplotype (0.406); a minority of cases with other haplotypes was also identified: atypical Bantu A2 (0.042), Senegal (0.031), atypical Bantu A7 (0.021) and Saudi Arabia/Indian (0.021) haplotypes; however, the Cameroon haplotype was not identified in this study. Our results are in agreement with the historical records that establish Sudanese and Bantu origins for the African slaves brought into Venezuela.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572002000100005
Editor: | Sociedade Brasileira de Genética
Relação: | 10.1590/S1415-47572002000100005
Formato: | text/html
Fonte: | Genetics and Molecular Biology  v.25 n.1 2002
Fonte: | info:eu-repo/semantics/openAccess