Data/hora: 17/06/2024 14:29:56

Provedor de dados: 	74	
País: 	Brazil	
Título: 	Association study of folate-related enzymes (MTHFR, MTR, MTRR) genetic variants with non-obstructive male infertility in a Polish population	
Autores: 	Kurzawski,Mateusz; Wajda,Anna; Malinowski,Damian; Kazienko,Anna; Kurzawa,Rafal; Drozdzik,Marek.	
Data: 	2015-03-01	
Ano: 	2015	
Palavras-chave: 	MTHFR; MTR; MTRR; Polymorphism; Infertility.	
Resumo: 	Spermatogenesis is a process where an important contribution of genes involved in folate-mediated one-carbon metabolism is observed. The aim of the present study was to investigate the association between male infertility and the MTHFR (677C &gt; T; 1298A &gt; C), MTR (2756A &gt; G) and MTRR (66A &gt; G) polymorphisms in a Polish population. No significant differences in genotype or allele frequencies were detected between the groups of 284 infertile men and of 352 fertile controls. These results demonstrate that common polymorphisms in folate pathway genes are not major risk factors for non-obstructive male infertility in the Polish population.	
Tipo: 	Info:eu-repo/semantics/report	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000100042	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-475738120140179	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.38 n.1 2015	
Fonte: 	info:eu-repo/semantics/openAccess