Data/hora: 02/06/2024 05:45:29

Provedor de dados: | Genetics and Molecular Biology
País: | Brazil
Título: | High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)
Autores: | García,Angelina; Dermarchi,Darío A.; Tovo-Rodrigues,Luciana; Pauro,Maia; Callegari-Jacques,Sidia M.; Salzano,Francisco M.; Hutz,Mara H.
Data: | 2015-09-01
Ano: | 2015
Palavras-chave: | AIMs; Córdoba; San Luis; Migration; Population structure.
Resumo: | The population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental markers and comparing the results with those previously obtained by us with mitochondrial DNA (mtDNA) in the same samples. A total of 521 healthy unrelated individuals living in 13 villages of the Córdoba and San Luis provinces were tested. The individuals were genotyped for ten autosomal ancestry informative markers (AIMs). Allele frequencies were compared with those of African, European and Native American populations, chosen to represent parental contributions. The AIM estimates indicated a greater influence of the Native American ancestry as compared to previous studies in the same or other Argentinean regions, but smaller than that observed with the mtDNA tests. These differences can be explained, respectively, by different genetic contributions between rural and urban areas, and asymmetric gene flow occurred in the past. But a most unexpected finding was the marked interpopulation genetic homogeneity found in villages located in diverse geographic environments across a wide territory, suggesting considerable gene flow.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000300324
Editor: | Sociedade Brasileira de Genética
Relação: | 10.1590/S1415-475738320140260
Formato: | text/html
Fonte: | Genetics and Molecular Biology  v.38 n.3 2015
Fonte: | info:eu-repo/semantics/openAccess