Data/hora: 10/06/2024 11:08:46

Provedor de dados: | Genetics and Molecular Biology
País: | Brazil
Título: | Expression of the bacterial recA gene impairs genetic recombination and sporulation in a Saccharomyces cerevisiae diploid strain
Autores: | Morais Junior,Marcos Antonio de; Santos,José Ferreira dos; Henriques,João Antonio Pegas.
Data: | 2003-01-01
Ano: | 2003
Palavras-chave: | DNA repair; Genetic recombination; RecA gene; Sporulation; Yeast.
Resumo: | The Escherichia coli RecA protein (RecAp) has been demonstrated to induce mutagenesis in yeast cells, although there is still little information on the role of the RecAp in yeast recombination events. We evaluated spontaneous and induced general recombination in vegetative and meiotic cells of the XS2316 strain of the yeast Saccharomyces cerevisiae bearing the recA gene. We found that RecAp decreased reciprocal recombination, gene conversion and intrachromosomal recombination and promoted an increase in error-prone processes in both vegetative and meiotic cells, while its negative effect on meiotic recombination blocked ascospore formation.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000200016
Editor: | Sociedade Brasileira de Genética
Relação: | 10.1590/S1415-47572003000200016
Formato: | text/html
Fonte: | Genetics and Molecular Biology  v.26 n.2 2003
Fonte: | info:eu-repo/semantics/openAccess