Data/hora: 09/06/2024 09:14:01

Provedor de dados: 	74	
País: 	Brazil	
Título: 	The Brazilian contribution to Attention-Deficit/Hyperactivity Disorder molecular genetics in children and adolescents	
Autores: 	Genro,Júlia Pasqualini; Roman,Tatiana; Rohde,Luis Augusto; Hutz,Mara Helena.	
Data: 	2012-01-01	
Ano: 	2012	
Palavras-chave: 	ADHD; Candidate genes; Pharmacogenetics.	
Resumo: 	Attention-Deficit/Hyperactivity Disorder (ADHD) is a common psychiatric condition of children worldwide. This disorder is defined by a combination of symptoms of inattention and hyperactivity/impulsivity. Diagnosis is based on a sufficient number of symptoms causing impairment in these two domains determining several problems in personal and academic life. Although genetic and environmental factors are important in ADHD etiology, how these factors influence the brain and consequently behavior is still under debate. It seems to be consensus that a fronto-subcortical dysfunction is responsible, at least in part, for the ADHD phenotype spectrum. The main results from association and pharmacogenetic studies performed in Brazil are discussed. The investigations performed so far on ADHD genetics in Brazil and elsewhere are far from conclusive. New plausible biological hypotheses linked to neurotransmission and neurodevelopment, as well as new analytic approaches are needed to fully disclose the genetic component of the disorder.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000600007	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572012000600007	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.35 n.4 suppl.1 2012	
Fonte: 	info:eu-repo/semantics/openAccess