Data/hora: 03/06/2024 18:48:54

Provedor de dados: 	74	
País: 	Brazil	
Título: 	First genotoxicity study of Paraná river water from Argentina using cells from the clam Corbicula fluminea (Veneroida Corbiculidae) and Chinese hamster (Cricetulus griseus Rodentia, Cricetidae) K1 cells in the comet assay	
Autores: 	Caffetti,Jacqueline D.; Mantovani,Mário S.; Pastori,María C.; Fenocchio,Alberto S.	
Data: 	2008-01-01	
Ano: 	2008	
Palavras-chave: 	Biomonitoring; Comet assay; Corbícula fluminea; CHO-K1 cells; Genotoxicity; Paraná river.	
Resumo: 	High concentrations of xenobiotics from urban and industrial wastes have contributed to the contamination of many aquatic environments. We used the comet assay to evaluate the genotoxic potential of water collected from the River Paraná, which receives a great deal of waste, at three points (Puerto Piray, Eldorado and Montecarlo) in the Misiones Province of Argentina. The in vivo comet assay used 40 freshwater clams (Corbicula fluminea) while the in vitro comet assay used Chinese hamster (Cricetulus griseus) K1 cell (CHO-K1) cultures with the mutagen ethyl methanesulfonate (EMS) as the positive control and phosphate buffered saline (PBS) as the negative control. Both assays showed statistically significant differences between the three sampling sites in relation to the negative control, the results of this preliminary study indicating that at these three sites water from the Paraná River presents genotoxic potential.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000300026	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572008000300026	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.31 n.2 2008	
Fonte: 	info:eu-repo/semantics/openAccess