Data/hora: 11/06/2024 07:24:27

Provedor de dados: 	Genetics and Molecular Biology	
País: 	Brazil	
Título: 	Change in genetic size of small-closed populations: lessons from a domestic mammal population	
Autores: 	Ghafouri-Kesbi,Farhad.	
Data: 	2010-01-01	
Ano: 	2010	
Palavras-chave: 	Pedigree; Effective size; Genetic drift; Genetic diversity; Genetic similarity; Sheep.	
Resumo: 	The aim of this study was to monitor changes in genetic size of a small-closed population of Iranian Zandi sheep, by using pedigree information from animals born between 1991 and 2005. The genetic size was assessed by using measures based on the probability of identity-by-descend of genes (coancestry, f, and effective population size, Ne), as well as measures based on probability of gene origin (effective number of founders, f e, effective number of founder genomes, f g, and effective number of non-founder genomes, f ne). Average coancestry, or the degree of genetic similarity of individuals, increased from 0.81% to 1.44% during the period 1993 to 2005, at the same time that Ne decreased from 263 to 93. The observed trend for f e was irregular throughout the experiment in a way that f e was 68, 87, 77, 92, and 80 in 1993, 1996, 1999, 2002, and 2005, respectively. Simultaneously, f g, the most informative effective number, decreased from 61 to 35. The index of genetic diversity (GD) which was obtained from estimates of f g,decreased about 2% throughout the period studied. In addition, a noticeable reduction was observed in the estimates of f ne from 595 in 1993 to 61 in 2005. The higher than 1 ratio of f e to f g indicated the presence of bottlenecks and genetic drift in the development of this population of Zandi sheep. From 1993 to 1999, f ne was much higher than f e, thereby indicating that with respect to loss of genetic diversity, the unequal contribution of founders was more important than the random genetic drift in non-founder generations. Subsequently, random genetic drift in non-founder generations was the major reason for f e&gt; f ne. The minimization of average coancestry in new reproductive individuals was recommended as a means of preserving the population against a further loss in genetic diversity.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000400011	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S1415-47572010000400011	
Formato: 	text/html	
Fonte: 	Genetics and Molecular Biology  v.33 n.4 2010	
Fonte: 	info:eu-repo/semantics/openAccess