Data/hora: 10/06/2024 16:59:39

Provedor de dados: | International Journal of Morphology
País: | Chile
Título: | Expression of PECAM-1 and E-Cadherin in the Umblical Cords of Gestational Diabetic Mothers
Autores: | Tahaoglu,A. E; Togrul,C; Külahcioglu,M. I; Bademkiran,M. H; Balsak,D; Mavi gök,E; Ekinci,C; Deveci,E.
Data: | 2015-12-01
Ano: | 2015
Palavras-chave: | Gestational diabetes mellitus; PECAM-1; Umblical cord; E-Cadherin.
Resumo: | The purpose of this study is to examine the changes in the umbilical cord in women diagnosed with gestational diabetes mellitus In this study, as a control group human placental tissues from normotensive pregnancies was collected from diabetic women at 28­35 weeks of gestation. Gestational diabetes (n= 20) and normal umbilical cord (n= 20) for a total of 40 units were received.GDM groups compared to the control group was significantly higher values was detected (p&lt;0.01). In GDM group, light microscopy showed erosion of the endothelium and complete rupture of theumbilicalvessels resulting in extravasation of blood within Wharton's jelly. it was observed that the cytoplasmic fragments and cell infiltration of the spill to the subepithelial layer of apoptotic cell PECAM-1 positive reaction showed. E-Cadherin in endothelial side surface of diabetes group showed weak expression in the nucleus and showed positive reaction in smooth muscle.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000400014
Editor: | Sociedad Chilena de Anatomía
Formato: | text/html
Fonte: | International Journal of Morphology  v.33 n.4 2015