Data/hora: 16/06/2024 05:12:25

Provedor de dados: | 77
País: | Chile
Título: | The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in Rats
Autores: | Turkozan,N. Y; Ulusoy,A. T; Balcioglu,H. A; Bal,F; Ozel,S.
Data: | 2009-09-01
Ano: | 2009
Palavras-chave: | Ovariectomy; Naproxen; Bone mineral density; Maximum load.
Resumo: | The goal of the present study was to investigate the effects of ovariectomy and naproxen treatment on both femoral and mandibular bone mass and biomechanical competence. Sprague-Dawley rats were used and divided into five groups: baseline, sham ovariectomized, ovariectomized, sham ovariectomized + naproxen treatment, ovariectomized + naproxen treatment. Mandibles and femurs of the rats were extracted and bone mineral density of the extracted specimens were determined. The volumes and ash weights of the femurs and mandibles were estimated. Maximum loads of the femurs and mandibles were determined by using a three point bending test. Ovariectomy decreased bone mineral density of the femoral midshaft, however naproxen prevented this decrease. Neither ovariectomy nor naproxen treatment affected the BMD in the molar alveolar region. Maximum load was found significantly decreased in the femoral midshaft, however, naproxen treatment prevented this decrease. Maximum load of the molar alveolar region did not significantly change. Naproxen prevents the strength characteristics of femoral midshaft afforded by ovariectomy. However, neither ovariectomy nor naproxen has an effect on the molar alveolar region of the mandible.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300007
Editor: | Sociedad Chilena de Anatomía
Formato: | text/html
Fonte: | International Journal of Morphology  v.27 n.3 2009