Data/hora: 17/06/2024 13:43:52

Provedor de dados: | 77
País: | Chile
Título: | Resistance of CA1 Pyramidal Cells to STZ-Induced Diabetes in Young Rats
Autores: | Fazeli,Seyyed Amirhossein; Gharravi,Anneh Mohammad; Jahanshahi,Mehrdad; Ghafari,Soraya; Behnampour,Naser; Golalipour,Mohammad Jafar.
Data: | 2009-12-01
Ano: | 2009
Palavras-chave: | Pyramidal cell density; CA1; Hippocampus; Diabetes; Rat.
Resumo: | The pyramidal cell density of CA1 hippocampal subfield following STZ-induced diabetes in young rats were studied. 12 male albino 6-week Wistar rats were allocated equally in groups of normal and diabetic. Hyperglycemia induced by Streptozotocin (80 mg/kg) in animals of diabetic group. After 5 weeks of study, all the rats were sacrificed and coronal sections were taken from dorsal hippocampal formation of the right cerebral hemispheres and stained with crysel violet. The area densities of the CA1 pyramidal cells were measured and compared among two groups. No significant difference between the densities of two experimental groups was found. The results can arise from the short period of diabetes and also the possible regenerative processes in developing brain of the young diabetic rats which compensated significant diabetes-induced neuronal loss.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400006
Editor: | Sociedad Chilena de Anatomía
Formato: | text/html
Fonte: | International Journal of Morphology  v.27 n.4 2009