Data/hora: 16/06/2024 11:16:35

Provedor de dados: | 77
País: | Chile
Título: | Evaluation of Some Biological Aspects of the Presence of Abrasive Silica and Thickening Silica  in Basic Formulations of Dentifrices
Autores: | Pedrazzi,Vinícius; Del Ciampo,José Orestes; do Nascimento,Cássio; Issa,João Paulo Mardegan.
Data: | 2009-03-01
Ano: | 2009
Palavras-chave: | Silica; Dentifrices; Histology; Wistar rats.
Resumo: | The aim of this study was to evaluate some biological characteristics and toxicity of basic formulations of dentifrices containing such substances, and to compare them with two existing products in market which also contains silic in their formulations. In this way, it was evaluated some biological parameters: weight of the animals, oral toxicity, hematological parameters, urinary analysis, and histological evaluation. The thrombocytes were also statistically at normal levels. The glutamate-pyruvate transaminase (TGP) showed normal aspect in 5 of the tested groups, as in control. Meanwhile, the oxalacetic transaminase (AST) in one group had a small increase in the control group. Regarding urine, in exception the rats of one group, the rats of the 4 other experimental groups showed leukocytosis urinary statistically higher than the control group. The histological evaluation of the animals showed that specimens from liver, stomach, kidney and submandibular gland presented normal aspects for these organs, without significant characteristics related to inflammatory infiltrates in any of the 6 samples tested in their respective groups.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000100028
Editor: | Sociedad Chilena de Anatomía
Formato: | text/html
Fonte: | International Journal of Morphology  v.27 n.1 2009