Data/hora: 09/06/2024 02:19:05

Provedor de dados: | 77
País: | Chile
Título: | Protective Effect of Curcumin Against Nicotine-induced Damage on Reproductive Parameters in Male Mice
Autores: | Jalili,C; Khani,F; Salahshoor,M. R; Roshankhah,S.
Data: | 2014-09-01
Ano: | 2014
Palavras-chave: | Curcumin; Nicotine; Reproductive Parameters; Mice.
Resumo: | Nicotine consumption can decrease fertility drive in males through inducing oxidative stress and DNA damage. The color of turmeric is because of a substance called curcumin for which some anti-oxidative and anti-inflammatory properties have been identified. In this study, various doses of curcumin (10, 30 and 60 mg/kg) and curcumin plus nicotine (10, 30 and 60 mg/kg) were administered intraperitoneally to male mice for 28 consequent days and reproductive parameters were determined. The results indicated that nicotine administration (0.5 mg/kg) significantly decreased testosterone level, count and motility of sperms, and testis weight compared to control group. However, increasing the dose of curcumin significantly increased reproductive indices in most of the groups. Thus, it seems that curcumin inhibits nicotine-induced adverse effects on reproductive parameters.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300017
Editor: | Sociedad Chilena de Anatomía
Formato: | text/html
Fonte: | International Journal of Morphology  v.32 n.3 2014