Data/hora: 08/06/2024 03:02:06

Provedor de dados: | Journal of Venomous Animals and Toxins
País: | Brazil
Título: | USE OF FIBRIN GLUE DERIVED FROM SNAKE VENOM IN TESTICULAR BIOPSY OF RAMS
Autores: | SARTORI FILHO,R.; PRESTES,N. C.; THOMAZINI,I. A.; MENDES-GIANNINI,M. J.; TOSCANO,E.; CANAVESSI,A. M. O.; BARRAVIERA,B.
Data: | 1998-01-01
Ano: | 1998
Palavras-chave: | Fibrin tecidual adhesive; Snake venoms; Biopsy; Testicle; Ovine.
Resumo: | Sequelae due to testicular biopsy such as hemorrhage, adhesion and fibrosis may be limiting factors to the use of this surgical procedure. Fibrin glue (FG) derived from snake venom was used to minimize these sequelae, as well as to evaluate its healing property in tunica vaginalis and scrotal skin of rams. Applicability of fibrin glue derived from snake venom was tested in different tissues of other animals such as in sciatic nerve and colon of rats and skin of rabbits. In the present study, 30 healthy adult rams were used. They were divided into 3 groups of 10 animals each as follows: G1: fibrin glue group (application of fibrin glue on puncture sites and skin incisions after bilateral testicular biopsy with a Tru-Cut needle); G2: swab/nylon group (hemostasis by compression with a swab on puncture sites and skin suturing with nylon after biopsy) and G3: control group (the animals were not subjected either to biopsy or to surgery). On the 20&lt;IMG SRC="Image485.gif" WIDTH=10 HEIGHT=17&gt; day after biopsy, the presence of adhesion strands between the sites of skin incision and testicle was evaluated by palpation. Adhesion strands were found in three testicles (15%) in G1 and in two testicles (10%) in G2. One hundred days after biopsy, orchiectomy was carried out and the material collected was assessed for subcutaneous (SC) and/or tunica vaginalis adhesions. G3 did not present any abnormality. Groups G1 and G2 presented four testicles each (20%) with adhesion between the tunics at biopsy site. On the other hand, subcutaneous adhesions were found once (5%) in G1 and three times (15%) in G2. Fibrin glue showed to be of easy application, required short postoperative monitoring, presented fast and good-quality healing property and tended to reduce formation of subcutaneous adhesion.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301998000100003
Editor: | Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP
Relação: | 10.1590/S0104-79301998000100003
Formato: | text/html
Fonte: | Journal of Venomous Animals and Toxins  v.4 n.1 1998
Fonte: | info:eu-repo/semantics/openAccess