Data/hora: 04/06/2024 05:44:57

Provedor de dados: | Neotropical Entomology
País: | Brazil
Título: | Transgenic mosquitoes for malaria control: progresses and challenges
Autores: | Moreira,Luciano A.; Jacobs-Lorena,Marcelo.
Data: | 2003-12-01
Ano: | 2003
Palavras-chave: | Malaria; Transgenesis; Transmission blocking; Plasmodium.
Resumo: | Malaria kills millions of people every year and the current strategies to control the disease, such as insecticides and drugs have not been completely efficient. Because of that, novel means to fight against malaria are of utmost importance. Advances in the study of the mosquito vector and its interactions with the malaria parasite made scientists think that it is possible to genetically manipulate the mosquitoes to make them inefficient vectors. Here we review the advances on the introduction of foreign genes into the mosquito germ line, the characterization of tissue-specific promoters, the identification of gene products that block development of the parasite in the mosquito, and we discuss the recent generation of transgenic mosquitoes impaired for malaria transmission. While much progress has been made, many years of research are still needed before transgenic mosquitoes can be used in the field.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-566X2003000400001
Editor: | Sociedade Entomológica do Brasil
Relação: | 10.1590/S1519-566X2003000400001
Formato: | text/html
Fonte: | Neotropical Entomology  v.32 n.4 2003
Fonte: | info:eu-repo/semantics/openAccess