Data/hora: 09/06/2024 06:22:39

Provedor de dados: | 86
País: | Brazil
Título: | Vitamin C and endogenous cortisol in foreign-body inflammatory response in pacus
Autores: | Belo,Marco Antonio de Andrade; Moraes,Julieta Rodini Engrácia de; Soares,Vando Edésio; Martins,Maurício Laterça; Brum,Camila Dantas; Moraes,Flávio Ruas de.
Data: | 2012-07-01
Ano: | 2012
Palavras-chave: | Piaractus mesopotamicus; Ascorbic acid; Glucocorticoid; Inflammation; Langhans cells; Multinucleated giant cells.
Resumo: | The objective of this work was to evaluate the effect of food supplementation with vitamin C on macrophage and multinucleated giant cell (MGC) activities of pacus at two stocking densities. The experiment was carried out in a 2x2x3 split-plot factorial arrangement with: 0 and 500 mg kg-1 vitamin C; 5 and 20 kg m-3 stocking densities; and evaluation times at 3, 6, and 12 days after the subcutaneous implantation of glass coverslips (DPI). The number of macrophages and MGC, as well as cortisol and glucose plasma levels were determined. The number of macrophages and MGC with two to five nuclei was significantly greater in fish supplemented with vitamin C at 5 kg m-3 stocking density at 3 DPI in comparison to nonsupplemented ones. The macrophage and MGC counts were lower in fish with high-plasma cortisol concentration. Supplementation with 500 mg vitamin C benefits macrophage activity on foreign-body inflammation, and high-cortisol concentration has suppressive effects on this response.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2012000700019

Editor:

Embrapa Secretaria de Pesquisa e Desenvolvimento

Pesquisa Agropecuária Brasileira

Relação: | 10.1590/S0100-204X2012000700019
Formato: | text/html
Fonte: | Pesquisa Agropecuária Brasileira  v.47 n.7 2012
Fonte: | info:eu-repo/semantics/openAccess