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Provedor de dados:  OAK
País:  Japan
Título:  A cutaneous mixed tumor in a dog
Autores:  Watanabe, Ken-ichi
Chambers, James K.
Uchida, Kazuyuki
Nibe, Kazumi
Ushio, Nanako
Horiuchi, Noriyuki
Kobayashi, Yoshiyasu
Nakayama, Hiroyuki
Data:  2017-03
Ano:  2017
Palavras-chave:  Cutaneous mixed tumor
Hair follicle
Multiphenotypic differentiation
Resumo:  The atypical cutaneous tumor of a 9-year-old mixed breed female dog was examined. The tumor was well-demarcated and histologically composed of a trichoblastic area, tricholemmal area and apocrine glandular area. Neoplastic cells in trichoblastic area and tricholemmal area had PAS-positive granules in the cytoplasm and were positive for pan-cytokeratin, cytokeratin 5/6, 14 and 19 and p63. Neoplastic cells in trichoblastic area were also positive for cytokeratin 15 and CD34. Neoplastic cells in apocrine glandular area were positive for pan-cytokeratin and cytokeratin 7,18 and 19. Myoepithelial cell proliferation with osteocartilaginous metaplasia was observed in this area. Since neoplastic cells showed multiphenotypic differentiation for hair follicles and apocrine glands, the present case was diagnosed as a cutaneous mixed tumor.
Idioma:  Inglês

Editor:  Japanese Society of Veterinary Science
Direitos:  This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License <>.

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