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Provedor de dados:  Anais da ABC (AABC)
País:  Brazil
Título:  Evidence of the Presence of Thyroid Hormones in Achatina fulica Snails
Autores:  LUSTRINO,DANILO
SILVA,ALBA C.M.
ARAUJO,IRACEMA G.
TUNHOLI,VICTOR M.
TUNHOLI-ALVES,VINÍCIUS M.
CASTRO,ROSANE N.
CARVALHO,DENISE P.
PINHEIRO,JAIRO
MARASSI,MICHELLE P.
Data:  2017-01-01
Ano:  2017
Palavras-chave:  Achatina fulica
Sodium/iodine symport
Thyroid hormones
Thyroglobulin
Resumo:  ABSTRACT The objective of this study was to identify thyroid hormones and to examine their putative site of synthesis in Achatina fulica snails. For this purpose, radioimmunoassays were performed for T3 and T4 before and after long starvation with or without hemolymph deproteinization. Sodium/iodide symporter activity in vivo was analyzed through 125I administration with and without KClO4 pretreatment. Only T4 was detected, and its concentration decreased due to starvation or deproteinization. However, high-performance liquid chromatography analysis also showed the presence of T2 and T3 apart from T4, but rT3 was not detected in the A. fulica hemolymph. The sodium/iodide symporter activity was greater in cerebral ganglia than digestive gland, but KClO4 treatment did not inhibit iodide uptake in any of the tissues analyzed. Altogether, our data confirm for the first time the presence of thyroid hormones in A. fulica snails and suggest their participation in the metabolism control in this species, although the putative site of hormone biosynthesis remains to be elucidated.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502181
Editor:  Academia Brasileira de Ciências
Relação:  10.1590/0001-3765201720160698
Formato:  text/html
Fonte:  Anais da Academia Brasileira de Ciências v.89 n.3 suppl.0 2017
Direitos:  info:eu-repo/semantics/openAccess
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