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Provedor de dados:  Anais da ABC (AABC)
País:  Brazil
Título:  Biomarkers as predictors of mortality in critically ill patients with solid tumors
Autores:  REIS,AUDREY M. DOS
FRUCHTENICHT,ANA V.G.
ATHAYDES,LUIZA C. DE
LOSS,SÉRGIO
MOREIRA,LUIS FERNANDO
Data:  2017-12-01
Ano:  2017
Palavras-chave:  Intensive care
Critically ill cancer patient
Intensive care mortality
Biochemical markers
Resumo:  ABSTRACT Biochemical markers produced by the affected organ or body in response to disease have gained high clinical value due to assess disease development and being excellent predictors of morbidity and mortality. The aim of this study is to analyze different biochemical markers in critically cancer patients and to determine which of them can be used as predictors of mortality. This is a prospective, cross-sectional study conducted at a University Hospital in Porto Alegre - RS. Screening was done to include patients in the study. Serum biochemical markers obtained in the first 24 hours of Intensive Care Unit hospitalization were analyzed. A second review of medical records occurred after three months objected to identify death or Unit discharged. A sample of 130 individuals was obtained (control group n = 65, study group n = 65). In the multivariate model, serum magnesium values ​​OR = 3.97 (1.17; 13.5), presence of neoplasia OR = 2.68 (95% CI 1.13; 6.37) and absence of sepsis OR = 0.31 (95% CI 0.12; 0.79) were robust predictors of mortality. The association of solid tumors, sepsis presence and alteration in serum magnesium levels resulted in an increased chance of mortality in critically ill patients.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000602921
Editor:  Academia Brasileira de Ciências
Relação:  10.1590/0001-3765201720170601
Formato:  text/html
Fonte:  Anais da Academia Brasileira de Ciências v.89 n.4 2017
Direitos:  info:eu-repo/semantics/openAccess
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