| Registro completo |
| Provedor de dados: |
ArchiMer
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| País: |
France
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| Título: |
Exploring the chemodiversity of tropical microalgae for the discovery of natural antifouling compounds
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| Autores: |
Réveillon, Damien
Tunin-ley, Alina
Grondin, Isabelle
Othmani, Ahlem
Zubia, Mayalen
Bunet, Robert
Turquet, Jean
Culioli, Gérald
Briand, Jean-françois
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| Data: |
2019-02
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| Ano: |
2019
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| Palavras-chave: |
Microalgae
Antifouling
Bioassay
Chemodiversity
Bioprospecting
Metabolomics
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| Resumo: |
Marine microalgae and cyanobacteria have largely been studied for their biotechnological potential and proved their ability to produce a wide array of bioactive molecules. We investigated the antifouling potential of unexplored benthic tropical microalgae using anti-adhesion and toxicity bioassays against two major micro- and ma crobiofoulers, namely bacteria and barnacles. Fifty strains belonging to six phyla [Cyanobacteria, Miozoa (Dinoflagellata), Bacillariophyta, Cryptophyta, Rhodophyta and Haptophyta] were isolated from southwestern Islands of the Indian Ocean. They were chosen in order to represent as much as possible the huge biodiversity of such a rich tropical ecosystem. The associated chemodiversity was highlighted by both NMR- and LC-MS-based metabolomics. The screening of 84 algal fractions revealed that the anti-adhesion activity was concentrated in methanolic ones (i.e. 93% of all active fractions). Our results confirmed that microalgae constitute a promising source of natural antimicrofoulants as 17 out of the 30 active fractions showed high or very high capacity to inhibit the adhesion of three biofilm-forming marine bacteria. Dinoflagellate-derived fractions were the most active, both in terms of number and intensity. However, dinoflagellates were also more toxic and may not be suitable as a source of environmentally friendly antifouling compounds, in contrast to diatoms, e.g. Navicula mollis. The latter and two dinoflagellates of the genus Amphidinium also had interesting anti-settlement activities while being moderately toxic to barnacle larvae. Our approach, combining the bioprospecting of a large number of tropical microalgae for their anti-settlement potential and metabolomics analyses, constituted a first step towards the discovery of alternative ecofriendly antifoulants.
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| Tipo: |
Text
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| Idioma: |
Inglês
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| Identificador: |
https://archimer.ifremer.fr/doc/00454/56608/58333.pdf
DOI:10.1007/s10811-018-1594-z
https://archimer.ifremer.fr/doc/00454/56608/
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| Editor: |
Springer Nature America, Inc
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| Formato: |
application/pdf
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| Fonte: |
Journal Of Applied Phycology (0921-8971) (Springer Nature America, Inc), 2019-02 , Vol. 31 , N. 1 , P. 319-333
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| Direitos: |
Springer Nature B.V. 2018
info:eu-repo/semantics/openAccess
restricted use
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