| Registro completo |
| Provedor de dados: |
BABT
|
| País: |
Brazil
|
| Título: |
Viability of Human Gingival Fibroblast (FGH) Treated with Ethanolic "Aroeira" Extract (Myracrodruon urundeuva Allemão)
|
| Autores: |
Machado,Alessandra Cury
Sartori,Patrícia Fernandes
Damante,Carla Andreotti
Dokkedal,Anne Lígia
Oliveira,Rodrigo Cardoso de
|
| Data: |
2016-01-01
|
| Ano: |
2016
|
| Palavras-chave: |
Medicinal Plant
Fibroblast
Myracrodruon urundeuva
"aroeira"
"aroeira-do-sertão"
|
| Resumo: |
ABSTRACT The aim of this study was to evaluate the effect of ethanolic "aroeira" (Myracrodruon urundeuva) extract on the viability of human gingival fibroblast. For this, fibroblasts (2x103 cells/well) were plated in a 96-well plate and incubated for 24 h; the medium (Eagle's medium modified by Dulbecco - DMEM) supplemented with 10% fetal bovine serum was replaced by DMEM with different ethanolic extract concentration (0, 0.1, 1, 10, 100, and 1000μg / mL). The fibroblast viability was analyzed after 48,72, and 96 h by the neutral red capture test and violet crystal. The "aroeira" extract, at high concentrations (100 and 1000 µg/mL) caused decrease in both cellular viability tests (p<0.05). However, dilutions between 0.1 and 10 µg/mL did not affect the viability of the cells. It was concluded that "aroeira" extract was able to change the gingival fibroblast viability, and this effect was concentration dependent.
|
| Tipo: |
Info:eu-repo/semantics/article
|
| Idioma: |
Inglês
|
| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100301
|
| Editor: |
Instituto de Tecnologia do Paraná - Tecpar
|
| Relação: |
10.1590/1678-4324-2016150335
|
| Formato: |
text/html
|
| Fonte: |
Brazilian Archives of Biology and Technology v.59 2016
|
| Direitos: |
info:eu-repo/semantics/openAccess
|
