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Provedor de dados:  BJID
País:  Brazil
Título:  Ventilator-associated pneumonia with Col-S strains: a successful comeback of colistin!
Autores:  Mukhopadhyay,C.
Data:  2008-10-01
Ano:  2008
Palavras-chave:  Colistin
Col-S strain
Ventilator-associated pneumonia
Resumo:  Emergence of multi and pan-drug resistant Gram-negative bacteria causing nosocomial infections in intensive care settings has become a challenge for clinicians. The mortality rate of ventilator-associated pneumonia (VAP) is known to increase when the initial microbiological diagnosis and antimicrobial therapy are inappropriate. We present a case of a 18-year-old man, who after being admitted following an accident, had developed VAP due to multi-drug resistant Pseudomonas aeruginosa and Acinetobacter spp. and had a downhill clinical course despite broad-spectrum antibiotic treatment. The strains were found to be Col-S, as the susceptibility was tested. Colistin was instituted, with remarkable recovery. It is imperative to diagnose VAP with multi-drug resistant strains as early as possible; colistin, the 'last resort' antibiotic, if instituted with proper monitoring at the right time, can be life saving.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Editor:  Brazilian Society of Infectious Diseases
Relação:  10.1590/S1413-86702008000500018
Formato:  text/html
Fonte:  Brazilian Journal of Infectious Diseases v.12 n.5 2008
Direitos:  info:eu-repo/semantics/openAccess

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