| Registro completo |
| Provedor de dados: |
BJID
|
| País: |
Brazil
|
| Título: |
Response to the complete hepatitis B vaccine regimen in infants under 12 months of age: a case series
|
| Autores: |
Miralha,Alexandre Lopes
Malheiro,Adriana
Miranda,Angélica Espinosa
Rutherford,George Williams
Alecrim,Maria das Graças Costa
|
| Data: |
2013-02-01
|
| Ano: |
2013
|
| Palavras-chave: |
Newborn infant
Prematurity
Hepatitis B vaccine
Seroconversion
|
| Resumo: |
OBJECTIVES: Describing rates of seroconversion and its associated factors in a series of Brazilian infants following the final dose of the vaccine at 6 months of age. METHODS: Peripheral blood samples were collected after the third dose of the vaccine for the detection of anti-hepatitis B surface antibodies among infants of 7-12 months of age. We measured the association between seroconversion and birthweight, gestational age, time since administration of the vaccine in the maternity hospital and whether or not testing for hepatitis B surface antigen had been performed during pregnancy. RESULTS: We examined 40 infants. The mean birthweight was 2787 g (standard deviation = 853 g) and mean gestational age was 37.5 (standard deviation = 3.08) weeks. The proportion that seroconverted was non-significantly higher in infants who weighed >2000 g at birth (96.7%) than in those with birthweights <2000 g (80%, p = 0.149). There was no difference between the infants who were born at <37 weeks of gestational age and those born at >37 weeks (p < 0.178) neither between seroconversion and the time of application of the first dose of the vaccine after delivery (p = 0.202). CONCLUSION: The proportion of infants who seroconverted was similar to that found in other Brazilian studies. There were no differences in the proportion seroconverting by age at first immunization.
|
| Tipo: |
Info:eu-repo/semantics/other
|
| Idioma: |
Inglês
|
| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000100013
|
| Editor: |
Brazilian Society of Infectious Diseases
|
| Relação: |
10.1016/j.bjid.2012.07.019
|
| Formato: |
text/html
|
| Fonte: |
Brazilian Journal of Infectious Diseases v.17 n.1 2013
|
| Direitos: |
info:eu-repo/semantics/openAccess
|
